Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo
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چکیده
منابع مشابه
Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo.
The acidic extracellular environment of tumors potentiates their aggressiveness and metastasis, but few methods exist to selectively modulate the extracellular pH (pHe) environment of tumors. Transient flushing of biological systems with alkaline fluids or proton pump inhibitors is impractical and nonselective. Here we report a nanoparticles-based strategy to intentionally modulate the pHe in t...
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ژورنال
عنوان ژورنال: Nanoscale
سال: 2016
ISSN: 2040-3364,2040-3372
DOI: 10.1039/c5nr06162h